Premium
Long‐term molecular differences between resilient and susceptible mice after a single traumatic exposure
Author(s) -
Pascual Cuadrado Diego,
Todorov Hristo,
Lerner Raissa,
Islami Larglinda,
Bindila Laura,
Gerber Susanne,
Lutz Beat
Publication year - 2022
Publication title -
british journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.432
H-Index - 211
eISSN - 1476-5381
pISSN - 0007-1188
DOI - 10.1111/bph.15697
Subject(s) - lipidome , transcriptome , microbiome , phenotype , traumatic stress , organism , biology , molecular neuroscience , psychology , bioinformatics , neuroscience , medicine , gene , clinical psychology , lipidomics , gene expression , genetics , receptor
Post-traumatic stress disorder (PTSD) is a heterogeneous disorder induced by trauma, resulting in severe long-term impairments of an individual's mental health. PTSD does not develop in every individual and, thus, some individuals are more resilient. However, the underlying molecular mechanisms are poorly understood. Here, we aimed to elucidate these processes.