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THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Ion channels
Author(s) -
Alexander Stephen P H,
Mathie Alistair,
Peters John A,
Veale Emma L,
Striessnig Jörg,
Kelly Eamonn,
Armstrong Jane F,
Faccenda Elena,
Harding Simon D,
Pawson Adam J,
Southan Christopher,
Davies Jamie A,
Aldrich Richard W.,
Attali Bernard,
Baggetta Austin M,
Becirovic Elvir,
Biel Martin,
Bill Roslyn M.,
Catterall William A.,
Conner Alex C.,
Davies Paul,
Delling Markus,
Virgilio Francesco Di,
Falzoni Simonetta,
Fenske Stefanie,
George Chandy,
Goldstein Steve A. N.,
Grissmer Stephan,
Ha Kotdaji,
Hammelmann Verena,
Hanukoglu Israel,
Jarvis Mike,
Jensen Anders A.,
Kaczmarek Leonard K.,
Kellenberger Stephan,
Kennedy Charles,
King Brian,
Kitchen Philip,
Lynch Joseph W.,
PerezReyes Edward,
Plant Leigh D.,
Rash Lachlan,
Ren Dejian,
Salman Mootaz M.,
Sivilotti Lucia G.,
Smart Trevor G.,
Snutch Terrance P.,
Tian Jinbin,
Trimmer James S.,
Van den Eynde Charlotte,
Vriens Joris,
Wei Aguan D.,
Winn Brenda T.,
Wulff Heike,
Xu Haoxing,
Yue Lixia,
Zhang Xiaoli,
Zhu Michael
Publication year - 2021
Publication title -
british journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.432
H-Index - 211
eISSN - 1476-5381
pISSN - 0007-1188
DOI - 10.1111/bph.15539
Subject(s) - clinical pharmacology , computer science , key (lock) , computational biology , pharmacology , world wide web , information retrieval , medicine , biology , computer security
The Concise Guide to PHARMACOLOGY 2021/22 is the fifth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of nearly 1900 human drug targets with an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. Although the Concise Guide constitutes over 500 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point-in-time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/bph.15539. Ion channels are one of the six major pharmacological targets into which the Guide is divided, with the others being: G protein-coupled receptors, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid-2021, and supersedes data presented in the 2019/20, 2017/18, 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the Nomenclature and Standards Committee of the International Union of Basic and Clinical Pharmacology (NC-IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate.