Premium
In vitro and in vivo characterization of the bifunctional μ and δ opioid receptor ligand UFP‐505
Author(s) -
Dietis N,
Niwa H,
Tose R,
McDonald J,
Ruggieri V,
Filaferro M,
Vitale G,
Micheli L,
Ghelardini C,
Salvadori S,
Calo G,
Guerrini R,
Rowbotham D J,
Lambert D G
Publication year - 2018
Publication title -
british journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.432
H-Index - 211
eISSN - 1476-5381
pISSN - 0007-1188
DOI - 10.1111/bph.14199
Subject(s) - agonist , receptor , pharmacology , opioid , morphine , chemistry , opioid receptor , in vivo , medicine , biology , biochemistry , microbiology and biotechnology
Targeting more than one opioid receptor type simultaneously may have analgesic advantages in reducing side-effects. We have evaluated the mixed μ opioid receptor agonist/ δ opioid receptor antagonist UFP-505 in vitro and in vivo.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom