Human secreted proteins  SLURP‐1  and  SLURP‐2  control the growth of epithelial cancer cells  via  interactions with nicotinic acetylcholine receptors | Zendy

Lyukmanova E N | Zendy; Bychkov M L | Zendy; Sharonov G V | Zendy; Efremenko A V | Zendy; Shulepko M A | Zendy; Kulbatskii D S | Zendy; Shenkarev Z O | Zendy; Feofanov A V | Zendy; Dolgikh D A | Zendy; Kirpichnikov M P | Zendy

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Human secreted proteins SLURP‐1 and SLURP‐2 control the growth of epithelial cancer cells via interactions with nicotinic acetylcholine receptors

Author(s) -

Lyukmanova E N,

Bychkov M L,

Sharonov G V,

Efremenko A V,

Shulepko M A,

Kulbatskii D S,

Shenkarev Z O,

Feofanov A V,

Dolgikh D A,

Kirpichnikov M P

Publication year - 2018

Publication title -

british journal of pharmacology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.432

H-Index - 211

eISSN - 1476-5381

pISSN - 0007-1188

DOI - 10.1111/bph.14194

Subject(s) - a431 cells , nicotinic agonist , skbr3 , receptor , cell growth , cancer cell , epidermal growth factor , microbiology and biotechnology , chemistry , biology , biochemistry , medicine , cancer , cell , cell cycle , oncogene , human breast

Nicotinic acetylcholine receptors (nAChRs) are a promising target for development of new anticancer therapies. Here we have investigated the effects of the endogenous human proteins SLURP-1 and SLURP-2, antagonists of nAChRs, on human epithelial cancer cells.

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