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Interferon γ treatment increases endocannabinoid and related N ‐acylethanolamine levels in T84 human colon carcinoma cells
Author(s) -
Alhouayek Mireille,
Rankin Linda,
GouveiaFigueira Sandra,
Fowler Christopher J
Publication year - 2019
Publication title -
british journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.432
H-Index - 211
eISSN - 1476-5381
pISSN - 0007-1188
DOI - 10.1111/bph.14135
Subject(s) - palmitoylethanolamide , anandamide , endocannabinoid system , fatty acid amide hydrolase , chemistry , pharmacology , biochemistry , biology , cannabinoid receptor , receptor , agonist
Endocannabinoids and related N-acylethanolamines (NAEs) are involved in regulation of gut function, but relatively little is known as to whether inflammatory cytokines such as IFNγ affect their levels. We have investigated this in vitro using cultures of T84 colon cancer cells.