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Neonicotinoid insecticides differently modulate acetycholine‐induced currents on mammalian α7 nicotinic acetylcholine receptors
Author(s) -
Cartereau Alison,
Martin Carine,
Thany Steeve H
Publication year - 2018
Publication title -
british journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.432
H-Index - 211
eISSN - 1476-5381
pISSN - 0007-1188
DOI - 10.1111/bph.14018
Subject(s) - clothianidin , neonicotinoid , thiamethoxam , nicotinic agonist , acetamiprid , pharmacology , imidacloprid , acetylcholine receptor , nicotinic acetylcholine receptor , acetylcholine , ganglion type nicotinic receptor , receptor , chemistry , biology , biochemistry , pesticide , agronomy
Neonicotinoid insecticides are described as poor agonists of mammalian nicotinic ACh receptors. In this paper, we show that their effects on mammalian nicotinic receptors differ between compounds.