Hydrogen sulfide pretreatment improves mitochondrial function in myocardial hypertrophy via a SIRT3‐dependent manner | Zendy

Meng Guoliang | Zendy; Liu Jieqiong | Zendy; Liu Shangmin | Zendy; Song Qiuyi | Zendy; Liu Lulu | Zendy; Xie Liping | Zendy; Han Yi | Zendy; Ji Yong | Zendy

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Hydrogen sulfide pretreatment improves mitochondrial function in myocardial hypertrophy via a SIRT3‐dependent manner

Author(s) -

Meng Guoliang,

Liu Jieqiong,

Liu Shangmin,

Song Qiuyi,

Liu Lulu,

Xie Liping,

Han Yi,

Ji Yong

Publication year - 2018

Publication title -

british journal of pharmacology

Language(s) - Italian

Resource type - Journals

SCImago Journal Rank - 2.432

H-Index - 211

eISSN - 1476-5381

pISSN - 0007-1188

DOI - 10.1111/bph.13861

Subject(s) - sirt3 , hydrogen sulfide , mitochondrion , myocardial hypertrophy , muscle hypertrophy , chemistry , medicine , biochemistry , endocrinology , pharmacology , enzyme , sirtuin , nad+ kinase , sulfur , organic chemistry

Hydrogen sulfide (H 2 S) is a gaseous signal molecule with antioxidative properties. Sirtuin 3 (SIRT3) is closely associated with mitochondrial function and oxidative stress. The study was to investigate whether and how H 2 S improved myocardial hypertrophy via a SIRT3-dependent manner.

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