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Mirabegron relaxes urethral smooth muscle by a dual mechanism involving β 3 ‐adrenoceptor activation and α 1 ‐adrenoceptor blockade
Author(s) -
Alexandre E C,
Kiguti L R,
Calmasini F B,
Silva F H,
Silva K P,
Ferreira R,
Ribeiro C A,
Mónica F Z,
Pupo A S,
Antunes E
Publication year - 2016
Publication title -
british journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.432
H-Index - 211
eISSN - 1476-5381
pISSN - 0007-1188
DOI - 10.1111/bph.13367
Subject(s) - mirabegron , vas deferens , prazosin , agonist , phenylephrine , endocrinology , medicine , silodosin , pharmacology , chemistry , receptor , antagonist , overactive bladder , prostate , lower urinary tract symptoms , alternative medicine , pathology , cancer , blood pressure
This article is commented on by Michel, M. C., pp. 429-430 of this issue. To view this commentary visit http://dx.doi.org/10.1111/bph.13379.