Does  PKC  activation increase the homologous desensitization of μ opioid receptors? | Zendy

Arttamangkul Seksiri | Zendy; Birdsong William | Zendy; Williams John T | Zendy

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Does PKC activation increase the homologous desensitization of μ opioid receptors?

Author(s) -

Arttamangkul Seksiri,

Birdsong William,

Williams John T

Publication year - 2015

Publication title -

british journal of pharmacology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.432

H-Index - 211

eISSN - 1476-5381

pISSN - 0007-1188

DOI - 10.1111/bph.12712

Subject(s) - muscarine , desensitization (medicine) , homologous desensitization , chemistry , μ opioid receptor , receptor , protein kinase c , hyperpolarization (physics) , enkephalin , locus coeruleus , damgo , agonist , staurosporine , endocrinology , medicine , biophysics , pharmacology , opioid , signal transduction , biology , biochemistry , muscarinic acetylcholine receptor , central nervous system , stereochemistry , nuclear magnetic resonance spectroscopy

This study examined the role of agents known to activate PKC on morphine-induced desensitization of μ-opioid receptors (MOP receptors) in brain slices containing locus coeruleus neurons.

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