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Anti‐inflammatory effects of cannabinoid CB 2 receptor activation in endotoxin‐induced uveitis
Author(s) -
Toguri J T,
Lehmann C,
Laprairie R B,
Szczesniak A M,
Zhou J,
DenovanWright E M,
Kelly M E M
Publication year - 2014
Publication title -
british journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.432
H-Index - 211
eISSN - 1476-5381
pISSN - 0007-1188
DOI - 10.1111/bph.12545
Subject(s) - cannabinoid , uveitis , pharmacology , cannabinoid receptor , cannabinoid receptor agonists , receptor , medicine , chemistry , neuroscience , biology , immunology , agonist
Cannabinoid CB2 receptors mediate immunomodulation. Here, we investigated the effects of CB2 receptor ligands on leukocyte-endothelial adhesion and inflammatory mediator release in experimental endotoxin-induced uveitis (EIU).