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Expression of histamine receptor genes Hrh3 and Hrh4 in rat brain endothelial cells
Author(s) -
Karlstedt K,
Jin C,
Panula P
Publication year - 2013
Publication title -
british journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.432
H-Index - 211
eISSN - 1476-5381
pISSN - 0007-1188
DOI - 10.1111/bph.12173
Subject(s) - receptor , histamine receptor , biology , microbiology and biotechnology , histamine , histamine h3 receptor , histamine h1 receptor , receptor antagonist , antagonist , endocrinology , biochemistry
Brain vascular endothelial cells express histamine H1 and H2 receptors, which regulate brain capillary permeability. We investigated whether H3 and H4 receptors are also expressed in these cells and may thus play a role in permeability regulation.