Open AccessMagnetic Resonance (MR) Metabolic Imaging in Glioma
Author(s) -
Chaumeil Myriam M.,
Lupo Janine M.,
Ronen Sabrina M.
Publication year - 2015
Publication title -
brain pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.986
H-Index - 132
eISSN - 1750-3639
pISSN - 1015-6305
DOI - 10.1111/bpa.12310
Subject(s) - magnetic resonance imaging , glioma , in vivo magnetic resonance spectroscopy , magnetic resonance spectroscopic imaging , medicine , neuroimaging , neuroscience , medical physics , nuclear magnetic resonance , nuclear medicine , radiology , biology , cancer research , physics
This review is focused on describing the use of magnetic resonance ( MR ) spectroscopy for metabolic imaging of brain tumors. We will first review the MR metabolic imaging findings generated from preclinical models, focusing primarily on in vivo studies, and will then describe the use of metabolic imaging in the clinical setting. We will address relatively well‐established 1 H MRS approaches, as well as 31 P MRS , 13 C MRS and emerging hyperpolarized 13 C MRS methodologies, and will describe the use of metabolic imaging for understanding the basic biology of glioma as well as for improving the characterization and monitoring of brain tumors in the clinic.