Open AccessA 50‐Year‐Old Man with Back Pain and A Sellar Mass
Author(s) -
Wilson Thomas C.,
Kirby Patricia A.
Publication year - 2013
Publication title -
brain pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.986
H-Index - 132
eISSN - 1750-3639
pISSN - 1015-6305
DOI - 10.1111/bpa.12053
Subject(s) - medicine , pituitary adenoma , skull , hepatocellular carcinoma , work up , craniopharyngioma , metastatic carcinoma , metastasis , pathology , radiology , pituitary gland , presentation (obstetrics) , carcinoma , adenoma , cancer , surgery , hormone
Hepatocellular carcinoma rarely metastasizes to the pituitary gland and this site is very rarely the initial site of disease presentation. When it does, it may mimic a far more common pituitary adenoma. Metastatic hepatocellular carcinoma should be suspected in any individual with known liver disease or significant risk factors. The most common clinical sign of metastatic HCC to the skull is a subcutaneous mass followed by neurological deficits including visual disturbances, headache and seizure. The diagnosis can be made based on the histopathologic and immunohistochemical findings. When metastatic HCC is present in the skull base, appropriate work up should be done to rule out other metastatic sites, most commonly present in the spine.