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Prevalence of urolithiasis among the Uyghur children of China: a population‐based cross‐sectional study
Author(s) -
Mai Zanlin,
Liu Yongda,
Wu Wenqi,
Aierken Ainiwaer,
Jiang Chonghe,
Batur Jesur,
Wusiman Sulitan,
Ma Jinxiang,
Li Yusi,
Xu Hai,
Ainiwa Aikebaier,
Saimaiti Saiding,
Tuerxun Aierken,
Zeng Guohua
Publication year - 2019
Publication title -
bju international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 1464-4096
DOI - 10.1111/bju.14776
Subject(s) - cross sectional study , china , medicine , population , demography , geography , environmental health , archaeology , sociology , pathology
Objectives To investigate the prevalence and associated factors of urolithiasis amongst Uyghur children. Subjects and Methods A cross‐sectional survey was conducted of Uyghur children (aged ≤14 years) in the Kashgar Region of China, from July to December 2016. Children were selected by a two‐stage random clustered sampling method, evaluated by urinary tract ultrasonography, low‐dose computed tomography (CT) examination, blood and urine analysis, and a questionnaire. The prevalence by CT, the prevalence by self‐report in the questionnaires, and the lifetime prevalence were evaluated. Binary logistic regression was used to estimate the associated factors. Results A total of 5605 children were selected and invited to participate in the study. In all, 4813 Uyghur children (2471 boys and 2342 girls), with an mean (SD; range) age of 75.79 (43.81; 2–177) months, were included in the final analysis, with a response rate of 85.9%. The prevalence of paediatric urolithiasis was 1.8% (95% confidence interval [CI] 1.5–2.2) by CT, 2.3% (95% CI 1.9–2.7) by self‐report, and 3.6% (95% CI 3.0–4.1) for the overall life‐time. The age‐sex adjusted prevalence was 2.0% (95% CI 1.6–2.4) by CT. Binary logistic regression analysis showed that body mass index, urinary tract infection, a family history of urolithiasis, and excessive sweating could increase the risk of stone formation, whilst breast feeding and drinking water at midnight could decrease the risk. Conclusions Urolithiasis is a major public health problem amongst Uyghur children, and strategies aimed at the prevention of urolithiasis are needed.