Central obesity is predictive of persistent storage lower urinary tract symptoms ( LUTS ) after surgery for benign prostatic enlargement: results of a multicentre prospective study

Objective To evaluate the impact of components of metabolic syndrome (MetS) on urinary outcomes after surgery for severe lower urinary tract symptoms ( LUTS ) due to benign prostatic enlargement ( BPE ), as central obesity can be associated with the development of BPE and with the worsening of LUTS . Patients and Methods A multicentre prospective study was conducted including 378 consecutive men surgically treated for large BPE with simple open prostatectomy ( OP ) or transurethral resection of the prostate ( TURP ), between January 2012 and October 2013. LUTS were measured by the International Prostate Symptom Score ( IPSS ), immediately before surgery and at 6–12 months postoperatively. MetS was defined according the USA National Cholesterol Education Program‐Adult Treatment Panel III . Results The improvement of total and storage IPSS postoperatively was related to diastolic blood pressure and waist circumference ( WC ). A WC of >102 cm was associated with a higher risk of an incomplete recovery of both total IPSS (odds ratio [ OR ] 0.343, P = 0.001) and storage IPSS ( OR 0.208, P < 0.001), as compared with a WC of <102 cm. The main limitations were: (i) population selected from a tertiary centre, (ii) Use exclusively of IPSS questionnaire, and (iii) No inclusion of further data. Conclusions Increased WC is associated with persistent postoperative urinary symptoms after surgical treatment of BPE . Obese men have a higher risk of persistent storage LUTS after TURP or OP .