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A prospective study of erectile function after transrectal ultrasonography‐guided prostate biopsy
Author(s) -
Murray Katie S.,
Bailey Jason,
Zuk Keegan,
LopezCorona Ernesto,
Thrasher J. Brantley
Publication year - 2015
Publication title -
bju international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 1464-4096
DOI - 10.1111/bju.13002
Subject(s) - medicine , biopsy , transrectal ultrasonography , prostate biopsy , urology , erectile dysfunction , prostate , erectile function , prospective cohort study , nocturnal penile tumescence , radiology , surgery , cancer
Objective To prospectively evaluate the effect of transrectal ultrasonography (TRUS)‐guided prostate biopsy on erectile and voiding function at multiple time‐points after biopsy. Patients and Methods All men who underwent TRUS‐guided prostate biopsy completed a five‐item version of the International Index of Erectile Function (IIEF‐5) and the International Prostate Symptom Score (IPSS) before and at 1, 4 and 12 weeks after TRUS‐guided biopsy. Statistical analyses used were a general descriptive analysis, continuous variables using a t ‐test and categorical data using chi‐square analysis. A paired t ‐test was used to compare each patient's baseline score to their own follow‐up survey scores. Results In all, 220 patients were enrolled with a mean age of 64.1 years and PSA level of 6.7 ng/dL. At initial presentation, 38.6% reported no erectile dysfunction (ED), 22.3% mild ED, 15.5% mild‐to‐moderate ED, 10% moderate ED, and 13.6% severe ED. On paired t ‐test there was a statistically significant reduction in IIEF‐5 score at 1 week after biopsy compared with before biopsy (18.2 vs 15.5; P < 0.001). This remained significantly reduced at 4 (18.4 vs 17.3; P = 0.008) and 12 weeks (18.4 vs 16.9, P = 0.004) after biopsy. Conclusions The effects of TRUS‐guided prostate biopsy on erectile function have probably been underestimated. It is important to be aware of these transient effects so patients can be appropriately counselled. The exact cause of this effect is yet to be determined.