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A merican U rological A ssociation ( AUA ) Guideline on prostate cancer detection: process and rationale
Author(s) -
Carter H. Ballentine
Publication year - 2013
Publication title -
bju international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 1464-4096
DOI - 10.1111/bju.12318
Subject(s) - guideline , medicine , prostate cancer , prostate cancer screening , asymptomatic , gynecology , prostate specific antigen , cancer , prostate , incidence (geometry) , oncology , intensive care medicine , pathology , physics , optics
To review the process and rationale for the A merican U rological A ssociation ( AUA ) guideline on prostate cancer detection. The AUA guideline on detection of prostate cancer involved a systematic literature review of >300 studies that evaluated outcomes important to patients (prostate cancer, incidence/mortality, health‐related quality of life, diagnostic accuracy and harms of testing). A multidisciplinary panel interpreted the evidence and formulated statements to assist the urologist and the asymptomatic average‐risk man in decision‐making about prostate cancer detection. Other than prostate‐specific antigen ( PSA )‐based prostate cancer screening, there was no evidence to address the outcomes of interest to patients. The strongest evidence that benefits may outweigh harms was in men aged 55–69 years undergoing PSA ‐based screening. This led the panel to recommend shared decision‐making for these men at average risk, but recommend against routine screening for other age groups at average risk. Further, to reduce the harms associated with screening (false positive tests, over diagnosis, over treatment), the panel recommended against annual screening for those who choose to be screened. A panel under the auspices of the AUA recommended shared decision‐making for the average risk asymptomatic man aged 55–69 years considering PSA ‐based screening for prostate cancer detection.

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