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Improving risk stratification in patients with prostate cancer managed by active surveillance: nomogram predicting the risk of biopsy progression
Author(s) -
Marks Leonard S.
Publication year - 2014
Publication title -
bju international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 1464-4096
DOI - 10.1111/bju.12306
Subject(s) - nomogram , medicine , prostate cancer , prostatectomy , watchful waiting , biopsy , occult , prostate specific antigen , risk stratification , cancer , pathological , oncology , pathology , alternative medicine
Active surveillance (AS) for low-risk prostate cancer has been widely embraced by the medical community, since its origins as a defined management strategy in the early 1990s [1]. Although as the present authors note, criteria for entry and intervention are yet to be standardised, virtually all authorities agree with the concept. And in fact, regardless of which published criteria are used, occult progression to advanced disease in compliant men is virtually unknown [2]. Importantly, when prostatectomy is performed after years of AS, pathological results are similar to those seen when operation is done de novo.