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Immunomodulatory drugs may overcome the negative prognostic role of active Th17 axis in follicular lymphoma: evidence from the SAKK35/10 trial
Author(s) -
Menter Thomas,
Hayoz Stefanie,
Zucca Emanuele,
Kimby Eva,
Dirnhofer Stefan,
Tzankov Alexandar
Publication year - 2020
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/bjh.16876
Subject(s) - follicular lymphoma , medicine , lymphoma , oncology , follicular phase , cancer research , immunology
(shown in Fig 1). Fig S3. Receiver operating characteristic (ROC) curves of Matutes score calculated using either A) FMC7% (area under the curve [AUC] 0.9994, 95% CI 0.999–1), B) CD20 MFI (AUC 0.9995, 95% CI = 0.999–1), or C) without FMC7 (AUC 0.996, 95% CI 0.993–0.999). For a threshold of 4 (A and B), sensitivity for the diagnosis of CLL was 100% (95% CI 98.4– 100) and 100% (95% CI 98.5–100) for A and B, respectively. Specificity was 97.1% (95% CI 94.3–98.7) and 98.1% (95% CI 95.7–99.3) for A and B, respectively. For a threshold of 3 (C), sensitivity for the diagnosis of CLL was 97.6% (95% CI 94.8–99.1) and specificity 98.9% (95% CI 96.9–99.8).