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Frailty score of older patients with haematological malignancies: unsuspected role of mild cognitive impairment
Author(s) -
Thibaud Vincent,
Piron Amandine,
Bron Dominique
Publication year - 2020
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/bjh.16469
Subject(s) - medicine , cognition , psychological intervention , cognitive impairment , intensive care medicine , geriatric oncology , gerontology , psychiatry , cancer
Summary Frailty assessment in older patients with haematological malignancies is extremely beneficial in order to optimize treatment decisions and supportive interventions. A comprehensive geriatric assessment can provide a better understanding of the functional age than clinical judgement by evaluating several skills domains such as physical function, autonomy, comorbidities, nutrition, cognition, psychological status and social support. However, the use of a multidisciplinary geriatric assessment may fail to detect unsuspected vulnerability such as mild cognitive impairment among so‐called “clinically fit” patients. The objective of this paper is to update the current knowledge about predictive factors for toxicity and “frailty scoring” in older patients with haematological malignancies. The unsuspected major role of cognitive impairment and how to detect it will be emphasized.