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Fatigue and cognitive impairment in immune thrombocytopenic purpura remain stable over time: short report from a longitudinal study
Author(s) -
Mitchell Eleanor,
Frith James,
Newton Julia
Publication year - 2019
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/bjh.15993
Subject(s) - medicine , immune thrombocytopenia , thrombocytopenic purpura , longitudinal study , platelet , immune system , purpura (gastropod) , cognition , pediatrics , immunology , psychiatry , pathology , ecology , biology
Summary Immune thrombocytopenic purpura ( ITP ) is an autoimmune disorder characterised by low platelet counts and increased bleeding risk. In 2009, two cross‐sectional studies determined that fatigue and cognitive impairment ( CI ) were common in ITP . Here, we report the results from a longitudinal study of 34 people with ITP . Fatigue severity remained unchanged over 7 years, and CI significantly improved. Future fatigue and CI severity could be predicted using baseline severity scores. These findings may be reassuring for ITP patients, as symptoms remain stable over time. Furthermore, using baseline scores to predict future severity could aid the clinical management of ITP .