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Self‐reported sleep disturbance and survival in myelodysplastic syndromes
Author(s) -
Luskin Marlise R.,
Cronin Angel M.,
Owens Robert L.,
DeAngelo Daniel J.,
Stone Richard M.,
Wadleigh Martha,
Steensma David P.,
Abel Gregory A.
Publication year - 2017
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/bjh.14573
Subject(s) - sleep disorder , sleep (system call) , disturbance (geology) , medicine , myelodysplastic syndromes , quality of life (healthcare) , physical therapy , gerontology , insomnia , psychiatry , biology , paleontology , bone marrow , nursing , computer science , operating system
Summary Neither the prevalence of sleep disturbance nor its association with fatigue and overall survival ( OS ) are well understood for patients with myelodysplastic syndromes ( MDS ). New patients at our institution ( n = 251; 2006–2014) completed the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire, which includes questions about sleep and fatigue. Fifty‐three per cent reported at least ‘a little’ trouble sleeping. In multivariable models, anaemia and sleep disturbance were associated with fatigue (both P < 0·001). Additionally, in separate models, sleep disturbance ( P = 0·002) and fatigue ( P = 0·04) both predicted OS . Our data suggest that improving sleep quality may impact MDS ‐related fatigue and OS .