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Morbidity and mortality of sickle cell disease patients starting intermittent haemodialysis: a comparative cohort study with non‐ Sickle dialysis patients
Author(s) -
Nielsen Louise,
CanouïPoitrine Florence,
Jais JeanPhilippe,
Dahmane Djamal,
Bartolucci Pablo,
Bentaarit Bouteina,
GellenDautremer Justine,
Remy Philippe,
Kofman Tomek,
Matig Marie,
Suberbielle Caroline,
Jacquelinet Christian,
WagnerBallon Orianne,
Sahali Dil,
Lang Philippe,
Damy Thibaud,
Galactéros Frédéric,
Grimbert Philippe,
Habibi Anoosha,
Audard Vincent
Publication year - 2016
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/bjh.14040
Subject(s) - medicine , dialysis , incidence (geometry) , sickle cell anemia , retrospective cohort study , disease , cohort , anemia , acute chest syndrome , cohort study , physics , optics
We performed a retrospective study to assess the changes in clinical, biological and heart echocardiographic parameters in 32 sickle cell disease ( SCD ) patients beginning haemodialysis. Acute SCD ‐related complications were similar at 6 months before and 6 months after the initiation of haemodialysis. Median haemoglobin level did not change significantly, but the need for blood transfusions increased ( P < 0·001). The 5‐year incidence of death was higher in SCD patients ( P < 0·0001). The 5‐year likelihood of receiving a renal graft was lower in SCD patients ( P = 0·022). Our findings suggest that SCD patients have poorer survival and a lower likelihood of receiving a renal graft.