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The AKT 1 isoform plays a dominant role in the survival and chemoresistance of chronic lymphocytic leukaemia cells
Author(s) -
Hofbauer Sebastian W.,
Krenn Peter W.,
Piñόn Hofbauer Josefina,
Pucher Susanne,
Asslaber Daniela,
Egle Alexander,
Hartmann Tanja N.,
Greil Richard
Publication year - 2016
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/bjh.13542
Subject(s) - akt2 , akt1 , protein kinase b , pi3k/akt/mtor pathway , cancer research , akt3 , chronic lymphocytic leukemia , idelalisib , bruton's tyrosine kinase , kinase , biology , stromal cell , ibrutinib , tyrosine kinase , signal transduction , immunology , microbiology and biotechnology , leukemia