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Combination of ibrutinib with ABT ‐199: synergistic effects on proliferation inhibition and apoptosis in mantle cell lymphoma cells through perturbation of BTK , AKT and BCL 2 pathways
Author(s) -
Zhao Xiaoxian,
Bodo Juraj,
Sun Danyu,
Durkin Lisa,
Lin Jeffrey,
Smith Mitchell R.,
Hsi Eric D.
Publication year - 2015
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/bjh.13149
Subject(s) - bruton's tyrosine kinase , mantle cell lymphoma , ibrutinib , apoptosis , cancer research , cell growth , chemistry , protein kinase b , lymphoma , microbiology and biotechnology , biology , signal transduction , immunology , biochemistry , leukemia , chronic lymphocytic leukemia , tyrosine kinase