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The current status of bridging anticoagulation
Author(s) -
Patel Jignesh P.,
Arya Roopen
Publication year - 2014
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/bjh.12644
Subject(s) - medicine , intensive care medicine , vitamin k antagonist , bridging (networking) , anticoagulant , clinical practice , vitamin k , clinical trial , surgery , warfarin , physical therapy , computer science , computer network , atrial fibrillation
Summary For patients prescribed chronic vitamin K antagonist therapy requiring a surgical or invasive procedure, the question of whether or not to bridge and how to bridge is commonly encountered in clinical practice. Bridging anticoagulation has evolved over the years and the evidence base for current practice is deficient in many areas. Clinical trials currently being completed with conventional anticoagulants should help strengthen the evidence base for future practice. The availability of novel oral anticoagulants is a welcome addition, though their optimal management peri‐procedure is yet to be determined. Prospective multi‐centre controlled studies that can provide the evidence base for novel oral anticoagulant peri‐procedural management are required.