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Measurement properties of the Rajka–Langeland severity score in children and adults with atopic dermatitis *
Author(s) -
Silverberg J.I.,
Lei D.,
Yousaf M.,
Janmohamed S.R.,
Vakharia P.P.,
Chopra R.,
Chavda R.,
Gabriel S.,
Patel K.R.,
Singam V.,
Kantor R.,
Hsu Derek Y.
Publication year - 2021
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/bjd.19159
Subject(s) - eczema area and severity index , medicine , atopic dermatitis , scorad , severity of illness , dermatology life quality index , quality of life (healthcare) , dermatology , pimecrolimus , discriminant validity , construct validity , physical therapy , internal consistency , psychometrics , psoriasis , clinical psychology , calcineurin , transplantation , nursing
Summary Background Multiple atopic dermatitis ( AD ) severity scales exist, with no gold standard for use in clinical practice. Objectives To determine the measurement properties of the Rajka–Langeland score and compare it with other clinician‐reported outcomes in adults and children with AD . Methods We performed a prospective dermatology practice‐based study using questionnaires and evaluation by a dermatologist ( n = 427). Results Rajka–Langeland had good concurrent validity with the Eczema Area and Severity Index (Spearman rho = 0·63), SCOR ing AD ( SCORAD ) (rho = 0·61), objective‐ SCORAD (rho = 0·52) and body surface area (rho = 0·51); good convergent validity with the numeric rating scale average‐itch (rho = 0·60) and worst‐itch (rho = 0·59), Patient‐Oriented Eczema Measure (rho = 0·57), Dermatology Life Quality Index (rho = 0·53), Patient‐Reported Outcomes Measurement Information System Itch Questionnaire (rho = 0·35–0·55) in adults and/or children; fair discriminant validity for patient‐ and physician‐reported global AD severity; good responsiveness to change of severity of AD and itch; good reliability; internal consistency; with no floor or ceiling effects. Interpretability bands (3, clear/almost clear; 4–5, mild; 6–7, moderate; 8–9, severe) and minimal clinically important difference (1 point) were established. Conclusions The Rajka–Langeland score showed good construct validity, reliability, internal consistency and responsiveness in adults and children with AD .