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Utility of the Pediatric Allergic Disease Quality of Life Questionnaire for childhood eczema
Author(s) -
Hon K.L.,
Ng W.G.G.,
Kung J.S.C.,
Cheng N.S.,
Ng D.K.K.,
Leung T.F.
Publication year - 2019
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/bjd.17710
Subject(s) - medicine , atopic dermatitis , quality of life (healthcare) , dermatology life quality index , asthma , disease , pediatrics , eczema area and severity index , severity of illness , dermatology , nursing
Summary Background Childhood atopic dermatitis ( AD ) is a chronic inflammatory disease associated with pruritus and sleep loss. It is important to evaluate quality‐of‐life (QoL) impairment objectively in atopic diseases in children. Objectives To investigate the utility of the Pediatric Allergic Disease Quality of Life Questionnaire ( PADQLQ ) in children with eczema. Methods PADQLQ , Patient‐Oriented Eczema Measure ( POEM , a short‐term subjective symptom score), Nottingham Eczema Severity Score ( NESS , a long‐term subjective symptom score) and Children's Dermatology Life Quality Index ( CDLQI , a short‐term subjective symptom score) were compared and correlations evaluated. Results PADQLQ , POEM , NESS and CDLQI correlated well with each other ( n = 132 sets; Spearman correlations: rho = 0·48–0·70, P < 0·001). A Bland–Altman plot showed a reasonably good agreement between CDLQI and PADQLQ . PADQLQ showed that symptoms of asthma, allergic conjunctivitis and allergic rhinitis were present in 20–30%, 45–71% and 58–67% of children with AD, respectively. Nevertheless, there was no association of eczema symptomatology by POEM or NESS with the severity of other allergic diseases. Conclusions PADQLQ correlates well with AD ‐specific severity and QoL scores and reflects all allergic symptoms that holistically influence QoL in children with AD . PADQLQ is hence a composite severity score in terms of clinical symptomatology and QoL impairment for AD .