z-logo
Premium
The global burden of melanoma: results from the Global Burden of Disease Study 2015
Author(s) -
Karimkhani C.,
Green A.C.,
Nijsten T.,
Weinstock M.A.,
Dellavalle R.P.,
Naghavi M.,
Fitzmaurice C.
Publication year - 2017
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/bjd.15510
Subject(s) - life expectancy , years of potential life lost , medicine , burden of disease , demography , disease burden , incidence (geometry) , epidemiology , disability adjusted life year , public health , mortality rate , disease , quality adjusted life year , global health , gerontology , environmental health , population , cost effectiveness , surgery , pathology , risk analysis (engineering) , physics , sociology , optics
Summary Background Despite recent improvements in prevention, diagnosis and treatment, vast differences in melanoma burden still exist between populations. Comparative data can highlight these differences and lead to focused efforts to reduce the burden of melanoma. Objectives To assess global, regional and national melanoma incidence, mortality and disability‐adjusted life year ( DALY ) estimates from the Global Burden of Disease Study 2015. Methods Vital registration system and cancer registry data were used for melanoma mortality modelling. Incidence and prevalence were estimated using separately modelled mortality‐to‐incidence ratios. Total prevalence was divided into four disease phases and multiplied by disability weights to generate years lived with disability ( YLD s). Deaths in each age group were multiplied by the reference life expectancy to generate years of life lost ( YLL s). YLD s and YLL s were added to estimate DALY s. Results The five world regions with the greatest melanoma incidence, DALY and mortality rates were Australasia, North America, Eastern Europe, Western Europe and Central Europe. With the exception of regions in sub‐Saharan Africa, DALY and mortality rates were greater in men than in women. DALY rate by age was highest in those aged 75–79 years, 70–74 years and ≥ 80 years. Conclusions The greatest burden from melanoma falls on Australasian, North American, European, elderly and male populations, which is consistent with previous investigations. These substantial disparities in melanoma burden worldwide highlight the need for aggressive prevention efforts. The Global Burden of Disease Study results can help shape melanoma research and public policy.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here