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In vivo reflectance confocal microscopy characterization of silver deposits in localized cutaneous argyria
Author(s) -
GarcíaMartínez P.,
López Aventín D.,
Segura S.,
GómezMartín I.,
Lloreta J.,
Ibáñez J.,
Elvira J.J.,
Pujol R.M.
Publication year - 2016
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/bjd.14571
Subject(s) - in vivo , pathology , dermis , confocal microscopy , papillary dermis , melanoma , microscopy , dermatoscopy , medicine , confocal , electron microscope , dermatology , optics , biology , cancer research , microbiology and biotechnology , physics
Summary Localized cutaneous argyria is a rare condition secondary to skin deposition of silver following exposure to substances containing this metal. The clinical appearance and dermoscopy findings require deep melanocytic lesions and particularly melanoma metastasis to be ruled out. Silver deposits are usually confirmed by scanning electron microscopy and/or energy‐dispersive X‐ray spectroscopy. Herein we describe the in vivo reflectance confocal microscopy ( RCM ) features observed in one case of localized cutaneous argyria. These features include the presence of a hyperrefractile network in the papillary dermis and a periadnexal dotted bright pattern. In vivo RCM might be a useful tool for an early diagnosis of this uncommon entity.