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Endothelial chimerism in chronic sclerotic‐type chronic graft‐versus‐host disease ( GVHD ) and GVHD ‐associated angiomatosis
Author(s) -
Kaffenberger B.H.,
Zhang E.,
Duncan J.R.,
Jaglowski S.,
Klisovic R.B.,
Devine S.M.,
Wong H.K.,
Gru A.A.
Publication year - 2016
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/bjd.14484
Subject(s) - angiomatosis , graft versus host disease , medicine , pathology , vascular disease , disease , immunology , chronic disease
Summary Graft‐versus‐host disease‐associated angiomatosis ( GVHD ‐ AA ) is an uncommon manifestation of chronic GVHD consisting of friable vascular proliferations. Using fluorescence in situ hybridization, we demonstrate the presence of donor‐derived endothelial cells within areas of GVHD ‐ AA . This is the first documented occurrence of a benign neoplastic growth in relationship to a form of chronic GVHD .