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Fistulizing Epstein–Barr virus‐positive plasmablastic lymphoma in an HIV ‐positive man
Author(s) -
Rangel J.,
Novoa R.,
Morrison C.,
Frank D.,
Kovarik C.
Publication year - 2016
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/bjd.14089
Subject(s) - plasmablastic lymphoma , lymphoma , immunophenotyping , medicine , malignancy , epstein–barr virus , virus , human immunodeficiency virus (hiv) , pathology , virology , immunology , antigen
Summary Plasmablastic lymphoma ( PBL ) is an unusual subtype of non‐Hodgkin lymphoma recently classified as a diffuse immunoblastic lymphoma with a plasma‐cell immunophenotype. Originally described in the oral cavity of HIV ‐positive patients, it has also been recognized to occur rarely at other sites. We describe a previously unreported fistulizing presentation of Epstein–Barr virus ( EBV )‐positive PBL , reviewing its association with HIV ‐1 infection and its importance as an AIDS ‐defining malignancy.