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Chronic cutaneous lichenoid graft‐versus‐host disease at the area of herpes zoster infection and at a vaccination site
Author(s) -
PalaciosAlvarez I.,
SantosBriz A.,
JorgeFinnigan C.,
Cañueto J,
FernandezLópez E.,
RomanCurto C.
Publication year - 2015
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/bjd.13894
Subject(s) - medicine , complication , varicella zoster virus , vaccination , graft versus host disease , disease , immunology , viral disease , virus , dermatology , virology , surgery , pathology
Summary Cutaneous graft‐versus‐host disease ( GVHD ) is a frequent complication of allogeneic bone marrow transplant and haematopoietic cell transplantation, but it is rarely presented as a Wolf's isotopic response. We report a patient who developed chronic lichenoid GVHD following the dermatomes previously affected by varicella zoster virus ( VZV ) infection. Nineteen months later, the same patient suffered from reactivation of GVHD at the injection site of an influenza vaccination. We review the literature concerning GVHD appearing after VZV infection and discuss the possible implications of this case and the pathogenic hypotheses.