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Reliability and validity of the Advanced Basal Cell Carcinoma Index ( aBCC dex)
Author(s) -
Mathias S.D.,
Chren M.M.,
Crosby R.D.,
Colwell H.H.,
Yim Y.M.,
Reyes C.,
Chen D.M.,
Fosko S.W.
Publication year - 2015
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/bjd.13877
Subject(s) - reliability (semiconductor) , exploratory factor analysis , medicine , construct validity , clinical psychology , scale (ratio) , internal consistency , basal cell carcinoma , population , psychometrics , oncology , basal cell , power (physics) , physics , environmental health , quantum mechanics
Summary Background Patient‐reported outcome ( PRO ) questionnaires were recently developed specifically for use with patients with advanced basal cell carcinoma ( aBCC ) and basal cell carcinoma naevus syndrome ( BCCNS ). Objectives To evaluate the measurement properties of PRO questionnaires for use in patients with aBCC or BCCNS . Methods In total 129 patients from 10 clinical sites in the U.S.A. and the BCCNS Support Network completed the two newly developed questionnaires multiple times over 3 months. Patients also completed the Skindex‐16 and the 12‐Item Short‐Form Health Survey as collateral measures. Psychometric properties of the questionnaires were evaluated, including internal consistency and test–retest reliability, construct and known‐groups validity, and responsiveness. Results Based on the results of exploratory factor analysis and clinical input, the two newly developed questionnaires were combined into a single questionnaire, called the aBCC dex, which is relevant for patients with both aBCC and BCCNS . The internal consistency reliability was acceptable, and all aBCC dex scale scores correlated significantly with conceptually similar scales. When divided into groups that differed based on scores from collateral measures, aBCC dex scale scores differentiated between groups (known‐groups validity) and were responsive to change. Conclusions The aBCC dex is a brief and comprehensive questionnaire appropriate for use with patients with aBCC and BCCNS . Its reliability and validity have been confirmed. Further research is necessary to estimate the minimally important difference in a larger patient population.