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Primary cutaneous T‐cell lymphoma presenting as mycosis fungoides with a T‐/null‐cell phenotype: report of two cases
Author(s) -
Bekel L.,
Chaby G.,
Lok C.,
Dadban A.,
Chatelain D.,
IngenHouszOro S.,
Ortonne N.
Publication year - 2015
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/bjd.13563
Subject(s) - mycosis fungoides , immunophenotyping , lymphoma , cutaneous t cell lymphoma , peripheral t cell lymphoma , medicine , cutaneous lymphoma , presentation (obstetrics) , pathology , dermatology , t cell lymphoma , null cell , t cell , biology , antigen , immunology , immune system , radiology , genetics , cell culture
Summary Variations in the clinical and histological presentation of cutaneous T‐cell lymphoma ( CTCL ) can hamper diagnosis. We report two cases of a novel presentation of CTCL characterized by an aberrant immunophenotype with complete loss of pan T‐cell antigens including T‐cell receptor β chain and showing the clinical and histopathological appearance of erythrodermic and plaque‐stage mycosis fungoides.