Premium
Comparing treatment goals for psoriasis with treatment decisions in daily practice: results from a prospective cohort of patients with psoriasis treated with biologics: Bio CAPTURE
Author(s) -
Zweegers J.,
Reek J.M.P.A.,
Kerkhof P.C.M.,
Otero M.E.,
Ossenkoppele P.M.,
Njoo M.D.,
Mommers J.M.,
Koetsier M.I.A.,
Arnold W.P.,
SybrandyFleuren B.A.M.,
Kuijpers A.L.A.,
Andriessen M.P.M.,
Kievit W.,
Jong E.M.G.J.
Publication year - 2014
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/bjd.13137
Subject(s) - biostatistics , medicine , psoriasis , cohort , family medicine , library science , dermatology , public health , pathology , computer science
Summary Background Treatment goals have been developed to optimize daily clinical practice psoriasis care, but have not yet been studied in real life. Objectives To investigate to what extent treatment decisions made by dermatologists in daily clinical practice for patients with psoriasis on biologics are already in accordance with treatment goals without the active application of the treatment goals algorithm. Methods Data were extracted from a prospective daily practice cohort of patients with psoriasis on biologics. Analysis was done on effectiveness (Psoriasis Area and Severity Index score) and quality of life (Dermatology Life Quality Index questionnaire). Treatment decisions such as dosage adjustments, combination treatments, or switching therapy were compared with the treatment goals algorithm. Results In 64% (253 of 395) of visits, physicians followed the treatment goals algorithm. There were 162 (41%) visits in which there should have been a treatment modification according to treatment goals (group Modify) and a modification was indeed made in 59 of these 162 visits (36%). In 233 (59%) visits no treatment modification was necessary (group Continue) and therapy was indeed not modified in 194 of 233 visits (83%). Conclusions Physicians acted in accordance with treatment goals in the majority of patient visits. In the patient group not achieving these goals, physicians should have modified therapy according to treatment goals but continued the same therapeutic regimen in the majority of visits. Optimizing therapy and defining barriers in the latter group might increase treatment results in daily practice psoriasis care.