Premium
Incidence of IgA vasculitis in the adult Slovenian population
Author(s) -
Hočevar A.,
Rotar Z.,
Ostrovršnik J.,
Jurčić V.,
Vizjak A.,
Dolenc Voljč M.,
Lindič J.,
Tomšič M.
Publication year - 2014
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/bjd.12946
Subject(s) - medicine , incidence (geometry) , vasculitis , confidence interval , population , pediatrics , disease , environmental health , physics , optics
Summary Background IgA vasculitis (Ig AV ) is assumed to be uncommon in adults. Objectives To determine the incidence rate of histologically proven Ig AV in the adult Slovenian population. Methods A retrospective chart review of adult patients diagnosed with Ig AV was performed at the departments of rheumatology, nephrology, infectious diseases and dermatovenereology at an integrated secondary/tertiary university teaching hospital. In order to avoid missing miscoded cases, the Institute of Pathology, University of Ljubljana, Slovenia, provided a list of all patients with an Ig AV ‐compatible histological pattern on biopsy. The annual incidence rate of histologically proven Ig AV was calculated. Results Eighty‐one new cases of Ig AV were identified from June 2010 to June 2013. The estimated annual incidence rate of Ig AV was 5·1 per 100 000 adults [95% confidence interval ( CI ) 3·4–7·4]; in men it was 6·1 per 100 000 (95% CI 3·9–10·6) and in women it was 3·7 per 100 000 (95% CI 1·8–6·8). Conclusions Although we only included histologically proven cases of Ig AV , the annual incidence rate of 5·1 per 100 000 adults is 3–6‐times higher than previously reported.