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Are patients with bipolar disorder and comorbid attention‐deficit hyperactivity disorder more neurocognitively impaired?
Author(s) -
Torres Imma,
Sole Brisa,
Corrales Montse,
Jiménez Esther,
Rotger Sofia,
SerraPla Juan Francisco,
Forcada Irene,
Richarte Vanesa,
Mora Ester,
Jacas Carlos,
Gómez Nuria,
Mur Maria,
Colom Francesc,
Vieta Eduard,
Casas Miquel,
MartinezAran Anabel,
Goikolea Jose M.,
RamosQuiroga Josep A.
Publication year - 2017
Publication title -
bipolar disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.285
H-Index - 129
eISSN - 1399-5618
pISSN - 1398-5647
DOI - 10.1111/bdi.12540
Subject(s) - neurocognitive , bipolar disorder , attention deficit hyperactivity disorder , executive functions , neuropsychology , psychology , cognitive impairment , cognition , psychiatry , clinical psychology , audiology , medicine
Objective Research on neurocognitive impairment in adult patients with comorbid bipolar disorder ( BD ) and attention‐deficit hyperactivity disorder ( ADHD ) is very scarce. This study assessed the neurocognitive profile of a comorbid group ( BD+ADHD ) compared with that of pure BD ( pBD ) group, pure ADHD ( pADHD ) group and healthy controls ( HC s). Methods This was a three‐site study comprising 229 subjects: 70 patients with pBD , 23 with BD + ADHD , 50 with pADHD , and 86 HC s. All patients with BD had been euthymic for at least 6 months. Neuropsychological performance was assessed using a comprehensive neurocognitive battery. Results Our results showed that all the clinical groups had poorer performance than the HC s in all the neurocognitive domains except for executive functions. No significant differences were observed between the pBD and BD + ADHD groups in any of the cognitive domains, with these two groups showing greater impairment than the pADHD group in executive functions and visual memory. Conclusions Our results, although preliminary, suggest that the BD + ADHD group showed the same neurocognitive profile as pBD patients, most likely reflecting the same neurobiological basis. On the other hand, the pADHD group showed a more selective moderate impairment in attention.