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Health equality, race and pharmacogenomics
Author(s) -
Magavern Emma F.,
Gurdasani Deepti,
Ng Fu L.,
Lee Sandra SooJin
Publication year - 2022
Publication title -
british journal of clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.216
H-Index - 146
eISSN - 1365-2125
pISSN - 0306-5251
DOI - 10.1111/bcp.14983
Subject(s) - pharmacogenomics , race (biology) , mainstream , health equity , health care , context (archaeology) , race and health , inclusion (mineral) , population health , medicine , population , public health , sociology , political science , social science , biology , environmental health , nursing , pharmacology , gender studies , paleontology , law
Pharmacogenomics is increasingly moving into mainstream clinical practice. Careful consideration must be paid to inclusion of diverse populations in research, translation and implementation, in the historical and social context of population stratification, to ensure that this leads to improvements in healthcare for all rather than increased health disparities. This review takes a broad and critical approach to the current role of diversity in pharmacogenomics and addresses potential pitfalls in order to raise awareness for prescribers. It also emphasizes evidence gaps and suggests approaches that may minimize negative consequences and promote health equality.