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Integrating anatomo‐physiological changes and pharmacogenomics in anti‐infective therapy management: is it a major concern?
Author(s) -
Beaumier Laura,
Chanoine Sébastien,
GautierVeyret Elodie,
Pluchart Hélène,
Cornet Muriel,
BrenierPinchart MariePierre,
Fonrose Xavier,
Camara Boubou,
Bedouch Pierrick
Publication year - 2019
Publication title -
british journal of clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.216
H-Index - 146
eISSN - 1365-2125
pISSN - 0306-5251
DOI - 10.1111/bcp.13785
Subject(s) - medicine , posaconazole , itraconazole , voriconazole , fluconazole , therapeutic drug monitoring , pharmacokinetics , pharmacology , alprazolam , adverse effect , antifungal , psychiatry , anxiety , dermatology
Success of anti-infective therapy is a major challenge in some patients given anatomo-physiological changes and genetic variations. In this case anecdote, we report the management strategy of a patient suffering from chronic pulmonary aspergillosis in a context of anorexia nervosa and genetic polymorphism.

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