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Issue highlights
Author(s) -
Elizabeth Whelan
Publication year - 2018
Publication title -
british journal of clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.216
H-Index - 146
eISSN - 1365-2125
pISSN - 0306-5251
DOI - 10.1111/bcp.13638
Subject(s) - medicine
Most pharmacokineticists are used to plasma as the preferred medium for the measurement of drug concentrations. Although a venipuncture is not a big deal for most it is a serious objection for pharmacokinetic research in children. So, non-invasive collection of bodily fluids is of interest to this group. Saliva is the obvious fluid, but little is known about the distribution kinetics of medicines to saliva. Laura Hutchinson and colleagues from Londonderry have done a useful systematic review about what is known as a guide for further research into what is not known.