Premium
What do we learn from repeated population analyses?
Author(s) -
Duffull Stephen B.,
Wright Daniel F. B.
Publication year - 2015
Publication title -
british journal of clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.216
H-Index - 146
eISSN - 1365-2125
pISSN - 0306-5251
DOI - 10.1111/bcp.12233
Subject(s) - population , value (mathematics) , medicine , computer science , environmental health , machine learning
Population analyses are performed on new and existing drugs. They play an important role in quantifying the time course of drug effects and provide a means of understanding the impact of variability between individuals on dosing requirements. For some drugs there have been several population analyses reported in the literature. It is important to understand how repeated population analyses can value add and what authors and readers can consider when reviewing such analyses. The purpose of this review is to explore what is learnt from repeated population analyses and provide an understanding of how the value‐added nature of these analyses can be considered.