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Granuloma formation and suspected neuropathic pain in a domestic pigeon ( C olumba livia ) secondary to an oil‐based, inactivated N ewcastle disease vaccine administered for protection against pigeon paramyxovirus‐1
Author(s) -
Cowan ML,
Monks DJ,
Raidal SR
Publication year - 2014
Publication title -
australian veterinary journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.382
H-Index - 59
eISSN - 1751-0813
pISSN - 0005-0423
DOI - 10.1111/avj.12173
Subject(s) - medicine , neuropathic pain , disease , dermatology , immunology , pathology , pharmacology
Case report A domestic pigeon developed a sterile granuloma following vaccination with an oil‐adjuvant, inactivated L a S ota strain of N ewcastle disease. The aim of vaccination was to provide protection against pigeon paramyxovirus‐1 ( PPMV ‐1), a disease previously considered exotic to A ustralia. Granuloma formation is considered a rare complication of vaccination against PPMV ‐1 in pigeons. Clinical signs consistent with neuropathic pain became apparent during the extensive management of the granuloma, which included surgical removal of foreign material, control of the pain and inflammation and protection against antimicrobial contamination. Conclusion PPMV ‐1 is now considered endemic in A ustralia and protecting pigeons with vaccination is important. Until a product is registered for use, vaccination remains off‐label and the risk of adverse reaction, including sterile granuloma, must be considered.