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Equine multinodular pulmonary fibrosis in three horses in A ustralia
Author(s) -
Spelta CW,
Axon JE,
Begg A,
Diallo ISI,
Carrick JB,
Russell CM,
Collins NM
Publication year - 2013
Publication title -
australian veterinary journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.382
H-Index - 59
eISSN - 1751-0813
pISSN - 0005-0423
DOI - 10.1111/avj.12072
Subject(s) - histopathology , horse , medicine , lung , pneumonia , pulmonary fibrosis , pathology , fibrosis , disease , biology , paleontology
Background Equine multinodular pulmonary fibrosis ( EMPF ) is a recently described form of interstitial pneumonia associated with the presence of equine herpesvirus type 5 ( EHV ‐5). Since 2007, several case reports from America, Europe and the U nited K ingdom have further characterised the clinical presentation and laboratory findings of this disease. Case reports Three Thoroughbred broodmares were diagnosed with EMPF . Diagnosis was based on lung histopathology and positive identification of EHV ‐5 using PCR DNA amplification. There was multiple organ involvement in all three cases, including identification of EHV ‐5 in hepatic tissue in one case. Two of the three horses died. Treatment with acyclovir was unsuccessful in one horse and one horse survived without antiviral or corticosteroid treatment. Conclusion This case series is, to the authors' knowledge, the first report of EMPF in A ustralia and adds to the clinical description of the disease.