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Identification of sialyl oligosaccharides including an oligosaccharide nucleotide in colostrum of an addax ( Addax nasomaculatus ) (Subfamily Antelopinae)
Author(s) -
Ganzorig Khuukhenbaatar,
Asakawa Takuya,
Sasaki Masashi,
Saito Tadao,
Suzuki Isao,
Fukuda Kenji,
Urashima Tadasu
Publication year - 2018
Publication title -
animal science journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.606
H-Index - 38
eISSN - 1740-0929
pISSN - 1344-3941
DOI - 10.1111/asj.12899
Subject(s) - colostrum , oligosaccharide , chemistry , biochemistry , bovidae , subfamily , lactose , biology , antibody , immunology , paleontology , gene
Mammalian milk/colostrum usually contains milk oligosaccharides along with the predominant lactose. Although milk oligosaccharides of a variety of Bovidae species including cow, sheep and goat have been characterized, those of the addax, an Antelopinae species of the Bovidae, have not as yet been clarified. In this study, several sialyl oligosaccharides were purified from a sample of addax colostrum and characterized as follows: Neu5Ac(α2‐8)Neu5Ac(α2‐3)Gal(β1‐4)Glc, Neu5Gc(α2‐8)Neu5Gc(α2‐3)Gal(β1‐4)Glc, Neu5Ac(α2‐3)Gal(β1‐4)Glc, Neu5Ac(α2‐6)Gal(β1‐4)Glc NA c, Neu5Gc(α2‐3)Gal(β1‐4)Glc, Neu5Gc(α2‐6)Gal(β1‐4)Glc, Neu5Gc(α2‐6)Gal(β1‐4)Glc NA c. In addition, an oligosaccharide nucleotide Neu5Gc(α2‐6)Gal(β1‐4)Glc NA cα1‐ UDP was characterized. Molecular species of a variety of sialyl oligosaccharides found in milk and colostrum of these Bovidae were compared.