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Synbiotics suppress the release of lactate dehydrogenase, promote non‐specific immunity and integrity of jejunum mucosa in piglets
Author(s) -
Andrejčáková Zuzana,
Sopková Drahomíra,
Vlčková Radoslava,
Kulichová Lucia,
Gancarčíková Soňa,
Almášiová Viera,
Holovská Katarína,
Petrilla Vladimír,
Krešáková Lenka
Publication year - 2016
Publication title -
animal science journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.606
H-Index - 38
eISSN - 1740-0929
pISSN - 1344-3941
DOI - 10.1111/asj.12558
Subject(s) - synbiotics , lactate dehydrogenase , lactobacillus fermentum , probiotic , biology , lactobacillus plantarum , jejunum , weaning , food science , breed , intestinal mucosa , andrology , microbiology and biotechnology , zoology , lactic acid , biochemistry , medicine , bacteria , enzyme , genetics
The aim of our experiment was to study how synbiotics are able to deal with the problems of post‐weaning piglets. Lactobacillus plantarum – Biocenol TM LP96 (CCM 7512), Lactobacillus fermentum – Biocenol TM LF99 (CCM 7514) and flaxseed (rich in n‐3 polyunsaturated fatty acids) were administered to 36 conventional piglets from a problematic breed with confirmed presence of enterotoxigenic Escherichia coli and Coronavirus . The experimental piglets were supplied with probiotic cheeses and crushed flax‐seed in the period starting 10 days before weaning and lasting up to 14 days post‐weaning. Piglets in the control group were supplied only control cheese. The impact of such additives on the release of lactate dehydrogenase (LDH; spectroscopic and electrophoretic assay), alteration of immunity (index of metabolic activity), jejunum histology (light microscopy), and health of conventional piglets from a problematic breed (monitoring of hematology, consistency and moisture of feces and body temperature) were examined. We found significant decrease in LDH leakage in the blood serum and tissue extracts, indicating better cell membrane integrity in the individual organs of animals. Probiotics and flaxseed applied together seem to be a good source of nutrients to improve the immune status and the integrity of jejunum mucosa during infection. © 2015 Japanese Society of Animal Science