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Effect of different levels of dietary sweet orange ( C itrus sinensis ) peel extract on humoral immune system responses in broiler chickens
Author(s) -
Pourhossein Zohreh,
Qotbi Ali Ahmad Alaw,
Seidavi Alireza,
Laudadio Vito,
Centoducati Gerardo,
Tufarelli Vincenzo
Publication year - 2015
Publication title -
animal science journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.606
H-Index - 38
eISSN - 1740-0929
pISSN - 1344-3941
DOI - 10.1111/asj.12250
Subject(s) - broiler , infectious bursal disease , immune system , bursa of fabricius , biology , titer , antibody titer , newcastle disease , antibody , virus , zoology , virology , immunology , biochemistry , virulence , gene
This experiment was conducted to evaluate the effects of different levels of sweet orange ( C itrus sinensis ) peel extract ( SOPE ) on humoral immune system responses in broiler chickens. Three hundred 1‐day broilers ( R oss‐308) were randomly allocated to treatments varying in supplemental SOPE added in the drinking water. The experimental groups consisted of three treatments fed for 42 days as follows: a control treatment without feed extract, a treatment containing 1000 ppm of SOPE and a treatment containing 1250 ppm of SOPE . All treatments were isocaloric and isonitrogenous. Broilers were vaccinated with N ewcastle disease virus ( NDV ), avian influenza ( AI ), infectious bursal disease ( IBD ) and infectious bronchitis virus ( IBV ) vaccines. Antibody titer response to sheep red blood cells ( SRBC ) was higher in the group fed 1250 ppm of SOPE ( P < 0.05) as well as for immunoglobulin G ( IgG ) and IgM . Similarly, antibody titer responses to all vaccines were constantly elevated ( P < 0.05) by SOPE enrichment in a dose‐dependent manner. Relative weights of spleen and bursa of Fabricius were unaffected by treatments. Dietary SOPE supplementation may improve the immune response and diseases resistance, indicating that it can constitute a useful additive in broiler feeding. Thus, supplying SOPE in rations may help to improve relative immune response in broiler chickens.