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Effects of a short pulse administration of Ulva rigida on innate immune response and intestinal microbiota in Sparus aurata juveniles
Author(s) -
AbdalaDíaz Roberto Teófilo,
GarcíaMárquez Jorge,
Rico Rosa María,
GómezPinchetti Juan Luis,
Mancera Juan Miguel,
Figueroa Félix L.,
Alarcón Francisco Javier,
MartínezManzanares Eduardo,
Moriñigo Miguel Ángel
Publication year - 2021
Publication title -
aquaculture research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.646
H-Index - 89
eISSN - 1365-2109
pISSN - 1355-557X
DOI - 10.1111/are.15148
Subject(s) - biology , algae , immune system , microbiology and biotechnology , respiratory burst , innate immune system , botany , immunology
Given the potential of algae as a new aquafeed ingredient, this study evaluated the effect of the tank‐cultivated macroalgae Ulva rigida C. Agardh (Chlorophyta) on innate immune response, intestinal microbiota and their resistance against Photobacterium damselae subsp. piscicida in juvenile gilthead seabream ( Sparus aurata L.) after a short pulse of administration. An algae‐free diet was used as control, and an experimental diet was formulated containing 25% of U. rigida (UL‐25). After 2, 7, 15 and 30 days biological samples were taken. No statistical significance ( p > 0.05) was detected in respiratory burst activity. Diet UL‐25 significantly enhanced alternative complement pathway activity respect to control diet from the beginning of the experiment ( p < 0.05). When fish were challenged against P. damselae subsp. piscicida , UL‐25‐fed fish were more resistant against the pathogen than the fish fed control diet, obtaining a relative survival percentage of 54.55%. The ability of UL‐25 diet to modify the intestinal microbiota was also confirmed. In conclusion, the use of a short pulse of dietary administration of 25% U. rigida in S. aurata diet modulates the immune response, intestinal microbiota and reduced the mortality rate during P. damselae subsp. piscicida infection.