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Effects of dietary betaine in allogynogenetic gibel carp ( Carassius auratus gibelio ): Enhanced growth, reduced lipid deposition and depressed lipogenic gene expression
Author(s) -
Dong Xiaojing,
Xue Wen,
Hua Jie,
Hang Yu,
Sun Longsheng,
Miao Shuyan,
Wei Wenzhi,
Wu Xinsheng,
Du Xuedi
Publication year - 2018
Publication title -
aquaculture research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.646
H-Index - 89
eISSN - 1365-2109
pISSN - 1355-557X
DOI - 10.1111/are.13652
Subject(s) - betaine , biology , carp , hepatopancreas , gene expression , endocrinology , biochemistry , lipid metabolism , medicine , food science , gene , fish <actinopterygii> , fishery
A 10‐week feeding experiment was conducted to evaluate the effects of supplemental betaine on growth performance, body composition and lipid deposition in allogynogenetic gibel carp. Four isoproteic (37% crude protein) and isolipidic (5% crude lipid) artificial diets with 0%, 0.08%, 0.4% and 2% betaine supplementation were formulated, and named VB 0 , VB 0.08 , VB 0.4 and VB 2 , respectively. Each diet was fed in triplicate to fish about 10 g in weight. The results showed that 0.4% betaine supplementation significantly improved growth performance and reduced lipid content in the hepatopancreas, muscle and the whole body compared with the control group. Moreover, both fatty acid synthase and acetyl‐CoA carboxylase, two important lipogenic genes, showed significantly lower expression in the VB 0.4 group than in the control group, and a strong correlation was detected between lipid content and mRNA expression levels for FAS and ACC in the hepatopancreas. Taken together, appropriate (0.4%) betaine supplementation in the diet not only improved growth, but also reduced lipid deposition in allogynogenetic gibel carp, probably by diminishing lipogenic gene expression.