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Dietary supplementation of sodium butyrate may benefit growth performance and intestinal function in juvenile grass carp ( Ctenopharyngodon idellus )
Author(s) -
Liu Mengmei,
Guo Wei,
Wu Fan,
Qu Qicai,
Tan Qingsong,
Gong Wangbao
Publication year - 2017
Publication title -
aquaculture research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.646
H-Index - 89
eISSN - 1365-2109
pISSN - 1355-557X
DOI - 10.1111/are.13230
Subject(s) - sodium butyrate , biology , hepatopancreas , grass carp , malondialdehyde , zoology , glutathione peroxidase , superoxide dismutase , antioxidant , weight gain , sodium , medicine , food science , endocrinology , biochemistry , body weight , chemistry , fishery , fish <actinopterygii> , gene , organic chemistry
A 49‐days feeding trial was conducted to study the effects of sodium butyrate on growth performance, gut morphology of juvenile grass carp. Five isoenergetic and isonitrogenous experimental diets were compounded by the supplementation in the basal diet with gradient sodium butyrate at 0, 500, 1000, 2000, 3000 mg kg −1 respectively. A total of 375 juvenile grass carp (with initial body weight of 3.8 g) were randomly allocated into five diet treatments, and each treatment has three replicates. The results showed that the specific growth rate ( SGR ) of SB 1000 and SB 2000 group was significantly higher ( P < 0.05) than that of the other groups. Moreover, the lowest SGR was observed in SB 3000 group. Feeding rate and the whole‐body proximate composition including moisture, crude lipid, crude protein and crude ash were not affected by sodium butyrate ( P > 0.05). Total superoxide dismutase activities in hepatopancreas in the experimental groups were significantly higher than those in the control group ( P < 0.05). Glutathione peroxidase activity in hepatopancreas was significantly upregulated by dietary sodium butyrate level ( P < 0.05). However, the activity of total antioxidant capacity and the contents of malondialdehyde were not significantly different among groups. The expression levels of mRNA encoding PepT1 and LAT 2 in the foregut both showed a first increasing and then decreasing tendency as dietary sodium butyrate level increased ( P < 0.05), and peaked in SB 1000 and SB 2000 groups respectively. The results indicated that appropriate dietary supplementation of sodium butyrate at 2000 mg kg −1 could improve the growth, antioxidant ability and intestinal absorption capacity of the juvenile grass carp.